Oncogenic osteomalacia

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Oncogenic osteomalacia

Severe osteomalacia (confirmed by the examination of thin undecalcified bone biopsy sections) associated with hypophosphataemia developed in a 60 year old woman. A skeletal x-ray survey showed a lytic lesion in the right proximal femur, and this was curetted, showing a vascular tumour. The patient's symptoms improved almost immediately and serum phosphate concentrations returned to normal. Some...

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Oncogenic osteomalacia.

Severe osteomalacia (confirmed by the examination of thin undecalcified bone biopsy sections) associated with hypophosphataemia developed in a 60 year old woman. A skeletal x-ray survey showed a lytic lesion in the right proximal femur, and this was curetted, showing a vascular tumour. The patient's symptoms improved almost immediately and serum phosphate concentrations returned to normal. Some...

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Oncogenic osteomalacia Case report

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized biochemically by hypophosphatemia, excessive urinary phosphate excretion, low 1,25-dihydroxyvitamin D levels, and clinically by osteomalacia, pseudofractures, bone pain, fatigue, and muscle weakness. TIO can occur in patients with a variety of benign mesenchimal tumors (hemangiopericitomas, fibromas, angiosarcomas,...

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Sinonasal Glomangiopericytoma Causing Oncogenic Osteomalacia

A 60-year-old woman suffered from recurrent femur neck fracture. Laboratory data showed serum hypophosphatemia, elevated alkaline phosphatase, normal serum calcium levels, and normal parathyroid hormone levels. Radiological examinations revealed a tumor in the right maxillary alveolar bone. The nasal cavity mass was removed, and the histological features were those of glomangiopericytoma. After...

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Nasal Hemangiopericytoma Causing Oncogenic Osteomalacia

Oncogenic osteomalacia is a rare cause that makes abnormalities of bone metabolism. Our case arose in a 47-year-old woman presenting a nasal mass associated with osteomalacia. We excised the mass carefully. After surgery, it was diagnosed as hemangiopericytoma and her symptoms related with osteomalacia were relieved and biochemical abnormalities were restored to normal range. We report and revi...

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ژورنال

عنوان ژورنال: QJM: An International Journal of Medicine

سال: 2018

ISSN: 1460-2725,1460-2393

DOI: 10.1093/qjmed/hcy004